TGF- inhibition: Inhibits transforming growth factor beta (TGF-), a key signal that causes hair follicles to prematurely enter the regression (catagen) phase
Supports neurotransmitter synthesis, is anti-inflammatory, and is especially useful for mood disorders, depression, dementia, PMS, skin disorders, and neuropathy
These effects suggest potential applications in peripheral neuropathies and traumatic nerve injuries, though human efficacy data remains limited
To the extent that melanotan II produces melanogenesis, this is thought to be caused by activation of the MC1 receptor, whereas its clinically documented sexual effects are thought to be related to its ability to activate the MC4 receptor (though the MC3 is thought to possibly also be involved)
In rodent studies, polyphenols from green tea significantly reduced IGF-1
Nutrients 12